SNAP-8 (Acetyl Octapeptide-3) is a synthetic octapeptide studied in topical anti-aging research as an elongated analog of Argireline, examined for its role in modulating SNARE complex assembly and the formation of expression lines. 10mg lyophilized, ≥99% purity confirmed by third-party COA.
SNAP-8 (Acetyl Octapeptide-3) is a synthetic octapeptide studied in topical anti-aging research as an elongated analog of Argireline, examined for its role in modulating SNARE complex assembly and the formation of expression lines. 10mg lyophilized, ≥99% purity confirmed by third-party COA. Bacteriostatic Water required for reconstitution.
In stock
10 MG
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Every batch independently third-party lab tested. Pharma-grade lyophilization. Shipped from our US facility within 24–48 hours.
≥99% HPLC purity
Every batch verified by an independent third-party lab. COA available on request and in the product gallery.
Pharma-grade lyophilization
Stable, shelf-ready powder. Reconstitute with bacteriostatic water for research use.
Ships in 24–48 hours
From our US facility. Cold-chain packaging on every order. Tracking provided on dispatch.
COA per batch
Certificate of Analysis for every lot. Identity, purity, and quality data — included in the product gallery.
About this compound
More on SNAP-8.
SNAP-8 from NXTSTATE is a research-grade peptide tested at ≥99% HPLC purity. A third-party Certificate of Analysis is included on every lot. Below you will find specifications, research applications, and the standards every shipment meets.
Product Overview
SNAP-8 (Acetyl Octapeptide-3) is a synthetic peptide composed of eight amino acids, developed as an elongated analog of Argireline (Acetyl Hexapeptide-8). The name refers to its research target: the SNAP-25 protein, a core component of the SNARE complex that governs vesicle fusion and neurotransmitter release. SNAP-8 has been studied primarily in topical and cosmetic science settings focused on the formation of expression lines.
NXTSTATE provides SNAP-8 in lyophilized form at research-grade purity, verified by independent HPLC and mass spectrometry analysis. Each vial includes a Certificate of Analysis.
Research Background
SNAP-8 is designed to mimic the N-terminal domain of SNAP-25 and compete with it during assembly of the SNARE complex. In published in vitro research, this competition destabilized complex formation and modulated calcium-dependent neurotransmitter release. Because SNARE-mediated acetylcholine release is a key signal in muscle contraction, SNAP-8 became a subject of interest in research on dynamic expression lines and the biochemistry of neuromuscular signaling.
Comparative studies have examined SNAP-8 alongside its shorter parent molecule, with research reporting greater activity for the octapeptide in SNARE inhibition assays. Additional cosmetic science research has evaluated SNAP-8 in emulsion and solution formats for topical delivery, skin penetration behavior, and formulation stability. Its favorable safety profile in research models and its biodegradable peptide structure have kept it among the most cited compounds in topical anti-aging peptide literature. Researchers studying skin aging frequently include SNAP-8 in comparative panels alongside copper peptides and other signal modulators.
Product Specifications
Molecular Formula: C41H70N16O16
Molecular Weight: ~1075.2 g/mol
Purity: ≥99% (HPLC verified)
Form: Lyophilized powder
Appearance: White powder
Storage: Store at -20°C for long-term, 2-8°C after reconstitution
Quality Assurance
NXTSTATE maintains strict quality control for all SNAP-8 inventory. Each batch is tested for purity via HPLC, confirmed by mass spectrometry, and screened for contaminants. Certificates of Analysis are included with every order.
Reconstitution and Handling
Reconstitute SNAP-8 with sterile water or bacteriostatic water in a clean laboratory environment. Store at 2-8°C after reconstitution and use within 30 days. Keep the lyophilized powder at -20°C until ready for use. Avoid repeated freeze-thaw cycles.
Compliance and Disclaimers
For Research Use Only (RUO)
Not for human consumption
Not intended to diagnose, treat, cure, or prevent any disease
Not approved for medical, cosmetic, food, or veterinary use
The buyer assumes all responsibility for proper handling, storage, and use
Must comply with all applicable local, state, and federal regulations
By purchasing this product, the buyer acknowledges it is being sold solely for research purposes and accepts all associated responsibility.
Related Research on SNAP-8
Researchers often pair SNAP-8 with complementary compounds in the NXTSTATE catalog, most notably GHK-Cu in skin biology work. Explore the full lab report library for third-party COAs on every lot, or browse the complete catalog for related research peptides. Independent peer-reviewed background is available through the PubMed research database.
Quality Standards Behind Every SNAP-8 Lot
Every lot leaving the NXTSTATE facility passes independent third-party HPLC testing. The Certificate of Analysis is matched to the batch number printed on each vial. Researchers can verify the COA before opening the package, then again at the bench. This level of transparency separates research-grade supply from grey-market sources.
Storage matters as much as sourcing. Each vial ships in lyophilized form with a desiccant pack and should be stored at -20°C until reconstituted. After reconstitution, refrigerate at 2-8°C. Following these conditions preserves potency throughout the research timeline. Cold-chain handling guidance ships with every order.
Related
Frequently asked
Common questions, answered.
Is this for human consumption?
No. All NXTSTATE products are sold strictly for laboratory research use only. They are not intended for human consumption, ingestion, or in vivo administration.
How is purity verified?
Every batch is independently tested by a third-party lab. The Certificate of Analysis confirms identity and ≥99% HPLC purity, and is included in the product gallery for every order.
How fast does it ship?
Orders placed before 2pm ET ship same-day. Most orders arrive in 24–48 hours within the US via expedited carrier. Tracking is sent on dispatch.
How should it be stored?
Lyophilized peptide should be stored sealed at room temperature, away from light and moisture. Once reconstituted with bacteriostatic water, refrigerate and use within 30 days.
What payment methods do you accept?
Visa, Mastercard, Zelle, Cash App, and Venmo. Card processing handled securely via our processor. Off-platform options (Zelle/CashApp/Venmo) available at checkout.