The KLOW Stack from NXTSTATE is a four peptide research blend supplied as a single 80mg lyophilized vial: GHK-Cu 50mg, BPC-157 10mg, TB-500 10mg and KPV 10mg. Every lot is sent for independent third-party HPLC testing, and the Certificate of Analysis is posted to our lab report library before a single vial ships.

Product Overview

KLOW Stack builds on the NXTSTATE Glow Stack formula (GHK-Cu, BPC-157 and TB-500) and adds KPV, a short anti-inflammatory tripeptide. The result is one vial that lets researchers study regenerative signaling and inflammatory signaling side by side, without reconstituting and tracking four separate compounds. Each component has its own independent body of published research, and KLOW Stack is designed for models that look at how those pathways interact.

Supplying the four peptides in fixed ratios also removes a common source of error in multi-compound work. The blend ratio is locked at the source, so every vial in a lot carries the same composition.

Research Background

GHK-Cu is a naturally occurring copper binding tripeptide studied for collagen and elastin synthesis, wound models and gene expression changes in skin and connective tissue. BPC-157 is a 15 amino acid fragment of a gastric protein that has been examined in tendon, ligament, gut and angiogenesis models. TB-500 is a synthetic form of the actin binding region of thymosin beta-4, researched for cell migration and tissue repair.

KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-melanocyte stimulating hormone. It has been studied for its effects on NF-kB signaling and inflammatory cytokines, particularly in intestinal and skin inflammation models. Researchers use KLOW Stack to examine whether combining a regenerative trio with an anti-inflammatory peptide changes outcomes compared with each compound alone. None of these peptides is approved for medical use.

Product Specifications

• Composition: GHK-Cu 50mg, BPC-157 10mg, TB-500 10mg, KPV 10mg
• Total Content: 80mg per vial
• GHK-Cu: Glycyl-L-histidyl-L-lysine copper complex, ~404 g/mol
• BPC-157: C₆₂H₉₈N₁₆O₂₂, ~1,419.5 g/mol
• KPV: Lys-Pro-Val tripeptide, ~342 g/mol
• Purity: Third-party HPLC report posted to the lab report library on release
• Form: Lyophilized powder
• Appearance: Light blue to white powder (copper content)
• Storage: Store at -20°C for long-term, 2-8°C after reconstitution

Quality Assurance

NXTSTATE does not release a new compound on a supplier’s word. This KLOW Stack lot is currently with an independent laboratory for HPLC purity testing and mass confirmation. When the report comes back it is matched to the batch number printed on each vial and published in full. Researchers on the waitlist are notified by email the moment the lot is cleared and in stock.

Reconstitution and Handling

Reconstitute KLOW Stack with bacteriostatic water in a clean laboratory environment, adding the diluent slowly down the side of the vial and swirling gently rather than shaking. Store at 2-8°C after reconstitution and use within 30 days. Keep the lyophilized powder at -20°C until ready for use and avoid repeated freeze-thaw cycles. The copper in GHK-Cu gives the reconstituted solution a faint blue tint, which is expected.

Compliance and Disclaimers

• For Research Use Only (RUO)
• Not for human consumption
• Not intended to diagnose, treat, cure, or prevent any disease
• Not approved for medical, cosmetic, food, or veterinary use
• The buyer assumes all responsibility for proper handling, storage, and use
• Must comply with all applicable local, state, and federal regulations

By purchasing this product, the buyer acknowledges it is being sold solely for research purposes and accepts all associated responsibility.

Related Research on KLOW Stack

Researchers often compare KLOW Stack against the Glow Stack and against single compounds such as GHK-Cu and KPV to separate the effect of each peptide. Explore the full lab report library for third-party COAs on every lot, or browse the complete catalog for related research compounds. Independent peer-reviewed background on KLOW Stack is available through PubMed.

Quality Standards Behind Every KLOW Stack Lot

Every lot leaving the NXTSTATE facility passes independent third-party HPLC testing. The Certificate of Analysis is matched to the batch number printed on each vial, so researchers can verify the report before opening the package and again at the bench. This level of transparency separates research-grade supply from grey-market sources.

Storage matters as much as sourcing. Each vial ships in lyophilized form and should be stored at -20°C until reconstituted, then refrigerated at 2-8°C. Following these conditions preserves potency throughout the research timeline. Handling guidance ships with every order.