Ipamorelin

Product Overview

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue (GHS) that selectively stimulates growth hormone release from the anterior pituitary gland. Unlike other GHS compounds, Ipamorelin is notable in research for its high selectivity, meaning it promotes GH release without significantly affecting other hormones such as cortisol, prolactin, or ACTH at typical research concentrations.

NXTSTATE provides Ipamorelin in lyophilized form at research-grade purity. Each vial undergoes independent HPLC and mass spectrometry verification, and ships with a Certificate of Analysis confirming purity, identity, and quality.

Research Background

Ipamorelin operates through the ghrelin/GHS receptor (GHS-R1a), the same receptor targeted by ghrelin and synthetic GHS compounds like GHRP-2 and GHRP-6. However, research has demonstrated that Ipamorelin achieves GH release with significantly fewer off-target effects, making it a preferred research tool for studying isolated GH pathway activity.

Published studies have investigated Ipamorelin in models of bone metabolism, body composition, gastrointestinal motility, and post-operative recovery. Research into its pharmacokinetic profile has shown a rapid onset of GH release with a relatively short duration of action, allowing precise temporal control in experimental protocols.

Ipamorelin is commonly studied in combination with CJC-1295, as the two compounds act through complementary mechanisms. CJC-1295 stimulates GH synthesis and release via the GHRH receptor, while Ipamorelin amplifies release via the GHS receptor. Researchers have investigated whether this dual-pathway approach produces additive or synergistic effects on GH pulsatility.

Product Specifications

• Molecular Formula: C₃₈H₄₉N₉O₅
• Molecular Weight: ~711.85 g/mol
• Purity: ≥99% (HPLC verified)
• Form: Lyophilized powder
• Quantity: 5mg per vial
• Appearance: White to off-white powder
• Storage: Store at -20°C for long-term, 2-8°C after reconstitution

Quality Assurance

NXTSTATE maintains rigorous quality standards for Ipamorelin. Each production batch is tested for purity via HPLC, confirmed by mass spectrometry for molecular identity, and screened for endotoxins and microbial contamination. Certificates of Analysis are included with every order.

Reconstitution and Handling

Reconstitute Ipamorelin with bacteriostatic water in a sterile laboratory environment. Inject the solvent slowly along the vial wall and gently swirl to dissolve. Once reconstituted, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles. The lyophilized powder should be stored at -20°C until ready for use.

Compliance and Disclaimers

• For Research Use Only (RUO)
• Not for human consumption
• Not intended to diagnose, treat, cure, or prevent any disease
• Not approved for medical, cosmetic, food, or veterinary use
• The buyer assumes all responsibility for proper handling, storage, and use
• Must comply with all applicable local, state, and federal regulations

By purchasing this product, the buyer acknowledges it is being sold solely for research purposes and accepts all associated responsibility.