In lab testing, results expected mid October. Join the waitlist and you will be emailed the moment it is in stock.

Sermorelin from NXTSTATE is a research-grade growth hormone releasing hormone analog supplied as a 5mg lyophilized vial. Every lot is sent for independent third-party HPLC testing, and the Certificate of Analysis is posted to our lab report library before a single vial ships. Below you will find specifications, research applications, and the standards every shipment meets.

Product Overview

Sermorelin, also called GHRH (1-29) or GRF 1-29, is a synthetic peptide made of the first 29 amino acids of human growth hormone releasing hormone. Those 29 residues are the shortest sequence that keeps the full biological activity of the native 44 amino acid hormone. Sermorelin binds the GHRH receptor on pituitary somatotroph cells and prompts them to release growth hormone.

Unlike direct growth hormone, Sermorelin works upstream, so release stays pulsatile and remains subject to the body’s normal feedback through somatostatin. That makes it a useful reference compound for studying the natural rhythm of the growth hormone axis.

Research Background

Sermorelin has one of the longest research histories of any growth hormone secretagogue. It was studied clinically for decades as a diagnostic and research tool for pituitary function, and a large body of published work describes its effects on growth hormone pulses, IGF-1 levels, sleep architecture and body composition.

Today researchers use Sermorelin as the baseline GHRH analog when comparing longer acting analogs such as CJC-1295 and Tesamorelin, and when studying how GHRH analogs combine with ghrelin receptor agonists like Ipamorelin. Sermorelin is sold here strictly for research use.

Product Specifications

• Sequence: GHRH (1-29) amide
• Molecular Formula: C₁₄₉H₂₄₆N₄₄O₄₂S
• Molecular Weight: ~3,358 g/mol
• Content: 5mg per vial
• Purity: Third-party HPLC report posted to the lab report library on release
• Form: Lyophilized powder
• Appearance: White powder
• Storage: Store at -20°C for long-term, 2-8°C after reconstitution

Quality Assurance

NXTSTATE does not release a new compound on a supplier’s word. This Sermorelin lot is currently with an independent laboratory for HPLC purity testing and mass confirmation. When the report comes back it is matched to the batch number printed on each vial and published in full. Researchers on the waitlist are notified by email the moment the lot is cleared and in stock.

Reconstitution and Handling

Reconstitute Sermorelin with bacteriostatic water in a clean laboratory environment, adding the diluent slowly down the side of the vial and swirling gently rather than shaking. Store at 2-8°C after reconstitution and use within 30 days. Keep the lyophilized powder at -20°C until ready for use and avoid repeated freeze-thaw cycles.

Compliance and Disclaimers

• For Research Use Only (RUO)
• Not for human consumption
• Not intended to diagnose, treat, cure, or prevent any disease
• Not approved for medical, cosmetic, food, or veterinary use
• The buyer assumes all responsibility for proper handling, storage, and use
• Must comply with all applicable local, state, and federal regulations

By purchasing this product, the buyer acknowledges it is being sold solely for research purposes and accepts all associated responsibility.

Related Research on Sermorelin

Researchers often study Sermorelin alongside Ipamorelin, CJC-1295 and Tesamorelin to compare short and long acting approaches to the growth hormone axis. Explore the full lab report library for third-party COAs on every lot, or browse the complete catalog for related research compounds. Independent peer-reviewed background on Sermorelin is available through PubMed.

Quality Standards Behind Every Sermorelin Lot

Every lot leaving the NXTSTATE facility passes independent third-party HPLC testing. The Certificate of Analysis is matched to the batch number printed on each vial, so researchers can verify the report before opening the package and again at the bench. This level of transparency separates research-grade supply from grey-market sources.

Storage matters as much as sourcing. Each vial ships in lyophilized form and should be stored at -20°C until reconstituted, then refrigerated at 2-8°C. Following these conditions preserves potency throughout the research timeline. Handling guidance ships with every order.