Product Overview

PT-141, also known as bremelanotide, is a synthetic cyclic seven amino acid peptide studied for its activity at melanocortin receptors, primarily MC3R and MC4R. It is a metabolite of Melanotan II, but where Melanotan II research centers on pigmentation pathways, PT-141 research focuses on central nervous system receptor signaling instead.

Each NXTSTATE vial contains 10mg of lyophilized PT-141 powder, tested by an independent third party laboratory before it reaches inventory. The lab report for this lot is published on this page. Check it before you buy.

Research Background

PT-141 appears across published neuroendocrine literature as a reference compound for melanocortin pathway research. Because it acts centrally at receptor sites rather than on the vascular system, researchers use it to study a mechanistically different pathway than vasodilator compounds, which is why it shows up so often in comparative receptor studies.

Its short cyclic structure also makes it a common subject in stability and delivery research. Related melanocortin research compounds are covered in our Research Notes.

Product Specifications

• Compound: PT-141 (bremelanotide)
• Quantity: 10mg per vial
• Purity: third party HPLC verified, lot report published on this page
• Form: Lyophilized powder
• Appearance: White to off-white powder
• Storage: Store lyophilized vials at -20C. Protect from light.
• Shipping: Ships from the US, typically within 24 hours

Quality Assurance

Every lot of PT-141 is tested by an independent third party lab for identity, quantity, and purity by RP-HPLC with UV detection. We publish the actual report, not a badge and not a promise. You can read it on this page before you spend a dollar.

If a company will not show you the lab report before you buy, that tells you something. Ours is right here.

Reconstitution and Handling

PT-141 is supplied as a lyophilized powder and is typically reconstituted with bacteriostatic water for laboratory use. Add solvent slowly against the vial wall and allow the powder to dissolve on its own without shaking. Store reconstituted material refrigerated and protected from light. Bacteriostatic water and syringes are available separately.

Why Researchers Study PT-141

Most compounds in this category act on one system. PT-141 is studied because it acts centrally, at melanocortin receptors in the nervous system, rather than peripherally on blood vessels. For a researcher designing a comparison, that distinction is the entire point: it isolates a receptor mediated pathway from a vascular one, so the two mechanisms can be examined separately instead of being confounded in the same model.

The peptide is also structurally compact and cyclic, which makes PT-141 a practical subject for stability work. Published PT-141 literature is indexed on PubMed under bremelanotide if you want to read the primary sources yourself before ordering.

Storage and Stability

Lyophilized PT-141 is stable for extended periods when stored correctly. Keep unopened vials at -20C, protected from light, and let a vial reach room temperature before opening it so condensation does not form on the powder. Once reconstituted, PT-141 should be refrigerated at 2C to 8C and kept away from light. Avoid repeated freeze and thaw cycles, which degrade peptides faster than storage temperature alone.

Handle vials gently. Peptides in solution are sensitive to mechanical stress, so swirl rather than shake, and do not vortex the solution.

Compliance and Disclaimers

This product is sold for laboratory and research use only. It is not a drug, supplement, or food, and it is not intended to diagnose, treat, cure, or prevent any disease. It is not for human or veterinary consumption. By purchasing PT-141 from NXTSTATE you confirm that you are a qualified researcher or institution and that this material will be handled only in an appropriate laboratory setting by trained personnel.